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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50034018'
Target
DNA topoisomerase 1
(Homo sapiens (Human))
Glaxo Inc. Research Institute
Curated by
ChEMBL
Ligand
BDBM50034018
((S)-4,11-Diethyl-4,N-dihydroxy-3,13-dioxo-3,4,12,1...)
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Affinity Data
IC50: 71nM
Assay Description:
Minimum concentration that produced 50% fragmentation of DNA was measured in the presence of excess calf thymus topoisomerase.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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Details
Article
PubMed
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