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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50036129'
Target
DNA topoisomerase 1
(Homo sapiens (Human))
Glaxo Research Institute
Curated by
ChEMBL
Ligand
BDBM50036129
(14-chloromethyl-7-ethyl-7-hydroxy-(7S)-7,8,11,13-t...)
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Affinity Data
IC50: 15nM
Assay Description:
Inhibition of topoisomerase I activity was determined in vitro by using the cleavable complex assay(calf thymus)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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