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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50036132'
Target
DNA topoisomerase 1
(Homo sapiens (Human))
Glaxo Research Institute
Curated by
ChEMBL
Ligand
BDBM50036132
(15-chloromethyl-8-ethyl-8-hydroxy-(8S)-2,3,8,9,12,...)
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Affinity Data
IC50: 11nM
Assay Description:
Inhibition of topoisomerase I activity was determined in vitro by using the cleavable complex assay(calf thymus)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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