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Found 1 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50045383'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045383((20S)-9,10-Dichloro-4-ethyl-4-hydroxy-1,12-dihydro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed