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Found 2 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50250996'
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50250996(CHEMBL525240 | TANNIN | chebulagic acid | chebulan...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human COLO201 cellular topoisomerase-1 mediated plasmid DNA cleavage by electrophoresis in presence of 14 units of enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50250996(CHEMBL525240 | TANNIN | chebulagic acid | chebulan...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human COLO201 cellular topoisomerase-1 mediated plasmid DNA cleavage by electrophoresis in presence of 70 units of enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed