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Found 2 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit A/B' and Ligand = 'BDBM50393079'
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  12nMAssay Description:The conversion of ATP to ADP by S. aureus TopoIV enzyme is coupled to the conversion of NADH to NAD+, and the progress of the reaction is measured by...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  28nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed