Found 2 Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM50459018' TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of DNAPK (unknown origin) using p53-based peptide substrate preincubated for 5 min prior to ATP additionMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DNAPK phosphorylation at Ser-2056 residue in human HT-29 cellsMore data for this Ligand-Target Pair
