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Found 2 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50328378'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328378(CHEMBL1258829 | ethyl 6-(3-cyclopentyl-1,2,4-oxadi...)
Affinity DataIC50: <30nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328378(CHEMBL1258829 | ethyl 6-(3-cyclopentyl-1,2,4-oxadi...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed