Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50341782'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human DGAT1 using 1,2-diacylglycerol/[14C]-oleoyl CoA as substrate assessed as [14C]-triglyceride formation after 10 mins by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  493nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed