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Found 2 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50358341'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358341(CHEMBL1922690)
Affinity DataIC50:  699nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358341(CHEMBL1922690)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed