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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM18047'
TargetDihydrofolate reductase(Candida albicans)
Gsk

LigandPNGBDBM18047(5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDI...)
Affinity DataIC50:  8nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Gsk

LigandPNGBDBM18047(5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDI...)
Affinity DataIC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed