Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50038261'
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  5.10E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equations 11...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  1.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  0.5nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with chicken dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  5.30E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equation 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  7.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  2.40E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with chicken dihydrofolate reductaseusing equations 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  7.10E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  0.600nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  5.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  6.90E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed