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Found 5 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50041177'
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed