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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50090050'
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50090050(1-(4-Fluoro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,...)
Affinity DataKi:  129nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50090050(1-(4-Fluoro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,...)
Affinity DataKi:  708nMAssay Description:Inhibitory activity against human lymphoblastoid cell (WIL2) dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50090050(1-(4-Fluoro-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,...)
Affinity DataKi:  2.24E+4nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed