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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50135135'
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135135(6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  830nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135135(6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135135(6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed