Affinity DataIC50: 0.550nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as susbtrateMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third
generation analogs were evaluated in enzyme inhibition assays, assessed
for S. aur...More data for this Ligand-Target Pair