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Found 6 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50329608'
TargetDihydrofolate reductase(Bacillus anthracis)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataKi:  4.28E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Candida Glabrata)
University of Connecticut

LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataIC50:  11nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Candida albicans)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Candida albicans DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataIC50:  290nMAssay Description:Enzyme activity assay were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over 5 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed