Found 1 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [491-589,Q498K,D521N,V555I,N579D]' and Ligand = 'BDBM12877' TargetDimer of Gag-Pol polyprotein [491-589,Q498K,D521N,V555I,N579D](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 0.0390nM ΔG°: -60.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
3D Structure (crystal)