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Found 7 Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50063372'
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Farnesyl protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  125nMAssay Description:Inhibition of Farnesyltransferase from Ras-CVLS or Ras-CVLL in Cos-7 monkey kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of Ha-ras farnesylation in Ha-ras-transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  6.50E+3nMAssay Description:In vitro inhibition of Ha-ras farnesylation in Ki-ras-transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  7.00E+3nMAssay Description:In vitro inhibition of Ha-ras farnesylation in DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063372(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibition of Ha-ras farnesylation in DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed