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Found 3 Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50063379'
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063379(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063379(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Farnesyl protein transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063379(1-[4-((S)-3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Farnesyltransferase from Ras-CVLS or Ras-CVLL in Cos-7 monkey kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed