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Found 3 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM11643'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11643((2S,5R)-1-((2S)-2-amino-2-cyclopentylethanoyl)-5-p...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11643((2S,5R)-1-((2S)-2-amino-2-cyclopentylethanoyl)-5-p...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM11643((2S,5R)-1-((2S)-2-amino-2-cyclopentylethanoyl)-5-p...)
Affinity DataKi:  56nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed