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Found 2 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50082939'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082939((2S,3S)-2-(4-Cyano-phenylsulfanyl)-N*4*-((S)-2,2-d...)
Affinity DataIC50:  0.630nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082939((2S,3S)-2-(4-Cyano-phenylsulfanyl)-N*4*-((S)-2,2-d...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TNF(tumor necrosis factor) in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed