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Found 3 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50171860'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataIC50:  230nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed