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Found 1 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q]' and Ligand = 'BDBM23458'
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM23458(hydroxamate deriv., 48 | propan-2-yl (1R,2R)-2-(hy...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed