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Found 4 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK1/CLK4' and Ligand = 'BDBM50239787'
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of HDAC1 expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of S6 kinase expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed