Found 6 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM317462'
Affinity DataIC50: 5nMAssay Description:Inhibition of CLK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human TTKMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of TTK in human CAL51 cells assessed as decrease in phosphorylated TTK T686 levels after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of TTK phosphorylation at T686 residue in human CAL51 cells after 1 hr by Western blot analysisMore data for this Ligand-Target Pair