Found 6 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM50349102' TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 0.630nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP®...More data for this Ligand-Target Pair
3D Structure (crystal)TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal 6XHis-tagged/GST-tagged full length human MPS1 expressed in recombinant baculovirus infected sf9 insect cells using 5FAM-DHT...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 8nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 160nMAssay Description:Inhibition of Myc-tagged wild type MPS1 autophosphorylation in human HCT116 cells after 2 hrs in presence of proteosome inhibitor MG132More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 182nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Netherlands Translational Research Center
US Patent
Netherlands Translational Research Center
US Patent
Affinity DataIC50: 182nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
