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Found 7 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM50081174'
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  17nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Escherichia coli using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  153nMAssay Description:Inhibition of NanoLuc-fused human DYRK1A expressed in HEK293 cells using Nano-Glo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Dyrk1A (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataKd:  2.60nMAssay Description:Binding affinity to human DYRK1A assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assayMore data for this Ligand-Target Pair