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Found 7 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B' and Ligand = 'BDBM50081174'
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataKi:  11nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  17nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  42nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
LigandPNGBDBM50081174(CHEMBL3421968)
Affinity DataIC50:  81nMAssay Description:Inhibition of NanoLuc-fused human DYRK1B expressed in HEK293T cells using Nano-Glo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair