Found 3 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM112761' TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human vasopressin V2 receptorMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
