Found 7 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50448936' 
Affinity DataIC50: 0.100nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum f...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.100nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay in presence of 15% h...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity to MDM2 in human SJSA1 cells assessed as upregulation of p21 mRNA expression after 7 hrs by qRT-PCR analysis in absence of human ser...More data for this Ligand-Target Pair
Affinity DataKd: 0.0360nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectrosco...More data for this Ligand-Target Pair
