Found 8 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50605405' TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 20:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 18:1 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 16:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 14:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
