BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Elongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor' and Ligand = 'BDBM50099062'

Elongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas

Curated by ChEMBL

BDBM50099062(CHEMBL3344081 | US10730870, Example 3 | US11512083...)

IC50: 800nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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3D Structure (crystal)