Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Endoplasmin' and Ligand = 'BDBM50087812'
TargetEndoplasmin(Canis familiaris)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKi:  440nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50:  32nMAssay Description:Inhibition of GRP94 (unknown origin) expressed in HEK293 cells assessed as reduction of Toll-like receptor trafficking to cell membrane treated for 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50:  1.14E+3nMAssay Description:Binding affinity to GRP94 N-domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50:  1.15E+3nMAssay Description:Displacement of FITC-GM from recombinant Grp94 (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of Cy3B-GM from recombinant Grp94 (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKd:  1.38E+3nMAssay Description:Inhibition of FITC-geldanamycin binding to canine GRP94 incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKd:  1.14E+3nMAssay Description:Apparent binding affinity to Grp94 (unknown origin) after 24 hrs by fluorescence polarization assay using FITC-GDA as tracerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed