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Found 2 Enz. Inhib. hit(s) with Target = 'Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM65515'
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Louisana

Curated by ChEMBL
LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Louisana

Curated by ChEMBL
LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells by cell based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed