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Found 4 Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM50443624'
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50:  3.33E+4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Mus musculus (Mouse))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50:  3.33E+4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...More data for this Ligand-Target Pair
In DepthDetails US Patent