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Found 4 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50032181'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity against endothelin A receptor from rabbit renal vascular smooth musclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of ET-1 stimulated arachidonic acid release in rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50032181(2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50:  8nMAssay Description:Inhibition of endothelin (ET-A) binding to porcine heart membranes More data for this Ligand-Target Pair
In DepthDetails Article