Found 2 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH] [T276S]' and Ligand = 'BDBM190656' TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University of Wurzburg
University of Wurzburg
Affinity DataKi: 3.00E+3nM ΔG°: -31.5kJ/molepH: 8.0 T: 2°CAssay Description:Steady-state kinetics were performed on a Cary 100 Bio (Varian) spectrometer at 25 °C using 30 mM PIPES, 150 mM NaCl, and 1.0 mM EDTA (pH 8.0) as...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis (Enterobacteria))
University of Wurzburg
University of Wurzburg
Affinity DataIC50: 3.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
