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Found 2 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI' and Ligand = 'BDBM8739'
LigandPNGBDBM8739(4-(4-methoxyphenyl)-1-[(4-methylphenyl)methyl]-1H-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Staphylococcus aureus FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM8739(4-(4-methoxyphenyl)-1-[(4-methylphenyl)methyl]-1H-...)
Affinity DataIC50:  360nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed