Found 10 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM250082' TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of EGFR (unknown origin) preincubated for 1 hr followed by Biotin-AVLESEEELYSSARQ-NH2 substrate addition in presence of ATP and measured a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of EGFR (unknown origin) preincubated for 1 hr followed by Biotin-AVLESEEELYSSARQ-NH2 substrate addition in presence of ATP and measured a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal DYKDDDD-tagged EGFR (669 to 1210 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as sub...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal DYKDDDD-tagged EGFR (669 to 1210 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as sub...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 606nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGFR phosphorylation at Tyr1068 residues preincubated for 1 hr followed by human EGF ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 606nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGFR phosphorylation at Tyr1068 residues preincubated for 1 hr followed by human EGF ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKd: 4.40E+3nMAssay Description:Binding affinity to EGFR (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataEC50: 390nMAssay Description:Inhibition of EGFR phosphorylation in human A-431 cellsMore data for this Ligand-Target Pair
