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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50022542'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022542(CHEMBL3297898 | US10189853, Compound 1)
Affinity DataIC50:  68nMAssay Description:Inhibition of EGFR in human A431 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022542(CHEMBL3297898 | US10189853, Compound 1)
Affinity DataIC50:  68nMAssay Description:Inhibition of EGFR in human A431 cells compound pretreated for 60 min before EGF stimulation for 10 mins by phosphotyrosine ELISA cytoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022542(CHEMBL3297898 | US10189853, Compound 1)
Affinity DataIC50:  68.2nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022542(CHEMBL3297898 | US10189853, Compound 1)
Affinity DataIC50:  82nMAssay Description:Inhibition of EGFR in human A431 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed