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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50040295'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-[(2,5-Dihydroxy-benzylidene)-amino]-2-hydroxy-be...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-[(2,5-Dihydroxy-benzylidene)-amino]-2-hydroxy-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50040295(5-[(2,5-Dihydroxy-benzylidene)-amino]-2-hydroxy-be...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER 22 (EGF-receptor expressing) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed