Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50154284'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: <200nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 336nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair