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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50179494'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50179494(CHEMBL3815163)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human EGFR expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50179494(CHEMBL3815163)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50179494(CHEMBL3815163)
Affinity DataIC50:  69nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50179494(CHEMBL3815163)
Affinity DataIC50:  76nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed