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Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM538135'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of EGFR Del19/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human EGFR del19/T790M/C797S mutant using ATP-labelled peptide substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human wild type EGFR using ATP-labelled peptide substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM538135(US11253516, Example 37)
Affinity DataIC50:  2.80nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent