BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-18,20-1210,T790M]' and Ligand = 'BDBM50029668'

Epidermal growth factor receptor [1-18,20-1210,T790M](Homo sapiens (Human))
Boehringer Ingelheim International

WIPO

BDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)

IC50: 1.60nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase DrugBank MCE
PC cid PC sid PDB Patents Similars

Details PubMed PDB

3D Structure (crystal)