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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-18,20-1210,T790M]' and Ligand = 'BDBM625593'
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory

US Patent
LigandPNGBDBM625593(US20230322822, Compound 5)
Affinity DataIC50:  1.90nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Homo sapiens (Human))
Chengdu Di''Ao Jiuhong Pharmaceutical Factory

US Patent
LigandPNGBDBM625593(US20230322822, Compound 5)
Affinity DataIC50:  38.1nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent