Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M,L858R]' and Ligand = 'BDBM313221'
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Jiangsu Medolution Ltd

US Patent
LigandPNGBDBM313221(N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-(tr...)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)cc1
Show InChI InChI=1S/C26H26F3N7O2/c1-3-23(38)31-19-5-4-6-20(15-19)32-24-22(26(27,28)29)16-30-25(34-24)33-18-7-9-21(10-8-18)36-13-11-35(12-14-36)17(2)37/h3-10,15-16H,1,11-14H2,2H3,(H,31,38)(H2,30,32,33,34)
Affinity DataKd:  0.540nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid