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Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM368197'
TargetEstrogen receptor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50:  0.210nMAssay Description:MCF-7 cells were adjusted to a concentration of 40,000 cells per mL in RPMI containing 10% FBS and 20 mM HEPES. 16 microliters of the cell suspension...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50:  0.300nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50:  0.300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein level after 4 hrs by InCell Western assayMore data for this Ligand-Target Pair