Found 20 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50238741' 
Affinity DataIC50: 0.25nMAssay Description:Antagonist activity at estrogen receptor in human T47D cells incubated for 18 hrs by ultra high sensitivity luminescence reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Downregulation of human ERalpha in human MCF-7 cells after 24 hrs by in-cell Western immunoassay methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Induction of ERalpha degradation in human T47D cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Induction of selective estrogen receptor alpha degradation in human MCF7 cells after 18 to 24 hrs by in-cell Western analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of fluoromone ligand from recombinant ER-alpha (unknown origin) by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Induction of selective estrogen receptor alpha degradation in human MCF7 cells harboring TK-ERE-Luc assessed as reduction in estradiol-induced transc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Induction of selective estrogen receptor alpha degradation in human MCF7 cells harboring TK-ERE-Luc assessed as reduction in estradiol-induced GREB1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estradiol-driven cell growth measured after 7 days by SYTOX green-based ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Downregulation of ER-alpha expression in human tamoxifen-resistant T47D cells over-expressing PKC-alpha measured after 5 days by Western blot analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Downregulation of ER-alpha expression in human T47D cells measured after 5 days by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal-stripped FBS incubated for 4 hrs by IRDye ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
Affinity DataKd: 4.70nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
